Summary

Here, we have proposed aptamer based electrochemical sensing platform for gut bacteria detection (H. pylori) which have important implications in gastric cancer. The detection of H. pylori is not yet focused as tool for diagnosis of these diseases. This aptamer based electrochemical detection technique is fast, sensitive and cost effective as compared to conventional techniques and antibodies-based biosensors. Moreover, present proposed method is non-invasive, cost effective, easy and fast for the detection of bacteria. So far, gut bacterium has not been used as biomarkers for the diagnosis of diseases. Moreover, their detection will be based on novel aptamer-based approach. This is the first proposal which aim the development of aptamer-based biosensor for gut bacteria detection. Also, the developed diagnostic sensing interface would allow H. pylori (gastric cancer) detection in early stage that would be a great contribution in clinical laboratories.